Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008550)
Formula
SVG example
N-acetylation
Reactant Etamicastat Product BIA 5-961
Reactant Info Product Info
Metabolic Enzyme N-acetyltransferase 2 (NAT2) DME Info
Metabolic Type Conjugation - N-acetylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008558 Etamicastat BIA 5-2311 Multi-steps Reaction - Deamination; oxidation Etamicastat [1]
MR008564 Etamicastat BIA 5-960 Unclear - Unclear Etamicastat [1]
MR008556 Etamicastat BIA 5-965 Multi-steps Reaction - Alkyl oxidation; deamination Etamicastat [1]
MR008561 Etamicastat BIA 5-998 Oxidation - Alkyl oxidation Etamicastat [1]
MR008563 Etamicastat Etamicastat metabolite M1 Unclear - Unclear Etamicastat [1]
MR008565 Etamicastat Etamicastat metabolite M19 Conjugation - Glucurono-conjugation Etamicastat [1]
MR008554 Etamicastat Etamicastat metabolite M3 Multi-steps Reaction - Deaminated; oxidated Etamicastat [1]
MR008562 Etamicastat Etamicastat metabolite M5 Unclear - Unclear Etamicastat [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008551 BIA 5-961 BIA 5-2320 Multi-steps Reaction - Desulfation; N-acetylation Etamicastat [1]
MR008553 BIA 5-961 BIA 5-2351 Conjugation - Glucurono-conjugation Etamicastat [1]
References
1 Human disposition, metabolism and excretion of etamicastat, a reversible, peripherally selective dopamine -hydroxylase inhibitor

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