Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008585)
Formula
SVG example
N-hydroxylation
Reactant Triapine Product Triapine metabolite M2
Reactant Info Product Info
Metabolic Type Oxidation - N-hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008583 Triapine Triapine metabolite M1 Oxidation - Dehydrogenation Triapine [1]
MR008586 Triapine Triapine metabolite M3 Unclear - Unclear Triapine [1]
MR008587 Triapine Triapine metabolite M4 Oxidation - N-hydroxylation Triapine [1]
MR008584 Triapine Triapine metabolite M5 Unclear - Unclear Triapine [1]
References
1 Understanding the metabolism of the anticancer drug Triapine: electrochemical oxidation, microsomal incubation and in vivo analysis using LC-HRMS

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