Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008683)
Formula
SVG example
Hydroxylation
Reactant Deoxydihydro-artemisinin Product Arteether Metabolite M1
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000302 Artemether Deoxydihydro-artemisinin Unclear Artemether [1]
MR008682 Dihydroqinghaosu (DQHS) Deoxydihydro-artemisinin Unclear - Unclear Arteether [2]
MR000315 2,3-dikeogulonic acid Deoxydihydro-artemisinin Unclear Ascorbic acid [3]
References
1 DrugBank(Pharmacology-Metabolism)Artemether
2 Synthesis, characterization, and antimalarial activity of the glucuronides of the hydroxylated metabolites of arteether
3 Ascorbic acid intake and oxalate synthesis Urolithiasis. 2016 Aug;44(4):289-97. doi: 10.1007/s00240-016-0868-7.

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