Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008827)
Formula
UGT2B7 ...
SVG example
Glucuronidation
Reactant Nalbuphine Product Nalbuphine-3-beta-D-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008825 Nalbuphine 3'-hydroxynalbuphine Oxidation - Hydroxylation Nalbuphine [1]
MR008826 Nalbuphine 4'-hydroxynalbuphine Oxidation - Hydroxylation Nalbuphine [1]
MR008828 Nalbuphine Nalbuphine-6-beta-D-glucuronide Conjugation - Glucuronidation Nalbuphine [1]
References
1 A dual system platform for drug metabolism: Nalbuphine as a model compound

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