Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008846)
Formula
SVG example
N-carbamoyl glucosidation
Reactant Varenicline Product Varenicline N-carbamoyl glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - N-carbamoyl glucosidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008848 Varenicline Hydroxyvarenicline Unclear - Unclear Varenicline [1]
MR008847 Varenicline N-formylvarenicline Conjugation - N-formyl conjugation Varenicline [1]
MR008845 Varenicline N-glucosyl varenicline Unclear - Unclear Varenicline [1]
MR008849 Varenicline Putative lactam Unclear - Unclear Varenicline [1]
References
1 Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro

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