Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008989)
Formula Reactant 2-OH-almotriptan Product Almogran metabolite A2
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008988 Almogran 2-OH-almotriptan Oxidation - Aliphatic hydroxylation Almogran [1]
MR000153 Almotriptan malate Almotriptan malate metabolite M3 Oxidation - Pyrrolidine Oxidation Almotriptan malate [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000146 Almotriptan malate metabolite M3 ACP-5461 Other reaction - Tautomerisation Almotriptan malate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008990 Almogran metabolite A2 Almogran metabolite P15 Unclear - Unclear Almogran [3]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.
2 Clinical pharmacokinetics of almotriptan, a serotonin 5-HT(1B/1D) receptor agonist for the treatment of migraine. Clin Pharmacokinet. 2005;44(3):237-46.
3 Almotriptan, a new anti-migraine agent: a review. CNS Drug Rev. 2002 Fall;8(3):217-34.

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