Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009448)
Formula
SVG example
Hydroxylation
Reactant GW1516-sulfone Product GW-501516 Metabolite M2
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009447 GW1516-sulfoxide GW1516-sulfone Oxidation - Oxidation GW-501516 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009455 GW1516-sulfone GW-501516 Metabolite M1 Unclear - Unclear GW-501516 [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009454 GW-501516 Metabolite M2 GW-501516 Metabolite M5 Unclear - Unclear GW-501516 [2]
MR009449 GW-501516 Metabolite M2 GW-501516 Metabolite M6 Unclear - Unclear GW-501516 [2]
References
1 Detection of PPAR agonists GW1516 and GW0742 and their metabolites in human urine
2 Metabolic study of GW1516 in equine urine using liquid chromatography/electrospray ionization Q-Exactive high-resolution mass spectrometry for doping control

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