Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009533)
Formula Reactant Rilpivirine M2 Product Rilpivirine M6
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009532 Rilpivirine hydrochloride Rilpivirine M2 Oxidation - Hydroxylation Rilpivirine hydrochloride [1]
References
1 Human biotransformation of the nonnucleoside reverse transcriptase inhibitor rilpivirine and a cross-species metabolism comparison. Antimicrob Agents Chemother. 2013 Oct;57(10):5067-79.

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