Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009540)
Formula
SVG example
Aromatic hydroxylation
Reactant Riluzole Product 5-OH-riluzole
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Metabolic Type Oxidation - Aromatic hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009543 Riluzole 2-Amino-6-OH-benzothiazole Unclear - Unclear Riluzole [1]
MR009539 Riluzole 4-OH-riluzole Oxidation - Aromatic hydroxylation Riluzole [1]
MR009541 Riluzole 7-OH-riluzole Oxidation - Aromatic hydroxylation Riluzole [1]
MR009542 Riluzole N-OH-riluzole Oxidation - N-oxidation Riluzole [1]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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