General Information of This Metabolic Reaction (MR) (ID: MR009724)
Formula
SVG example
Unclear
Reactant Motesanib M5 Product Motesanib M4
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009723 Motesanib Motesanib M5 Oxidation - Hydroxylation Motesanib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009726 Motesanib Motesanib M4 Unclear - Unclear Motesanib [1], [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009725 Motesanib M4 Motesanib Miv Unclear - Unclear Motesanib [1]
References
1 In vitro metabolism of the novel, highly selective oral angiogenesis inhibitor motesanib diphosphate in preclinical species and in humans
2 Population pharmacokinetic modeling of motesanib and its active metabolite, M4, in cancer patients

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