Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR009850)
Formula	Unclear
	Reactant	4-hydroxymethyl?ambrisentan		Product	4-hydroxymethyl?ambrisentan glucuronide
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009849	Ambrisentan	4-hydroxymethyl?ambrisentan	Oxidation - Oxidation	Ambrisentan	[1], [2]

References
1	Effect of ketoconazole on the pharmacokinetic profile of ambrisentan. J Clin Pharmacol. 2009 Jun;49(6):719-24.
2	Potential for pharmacokinetic interactions between ambrisentan and cyclosporine. Clin Pharmacol Ther. 2010 Oct;88(4):513-20.

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