Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009994)
Formula Reactant 4-dimethylamino-22-diphenylvaleric acid Product 4-methylamino-2,2-diphenylvaleric acid
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009993 Methadone 4-dimethylamino-22-diphenylvaleric acid Unclear - Unclear Methadone [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009995 4-methylamino-2,2-diphenylvaleric acid 15-dimethyi-33-diphenyl-2-pyrrolidone Unclear - Unclear Methadone [1], [2]
References
1 Methadone metabolism and drug-drug interactions: in vitro and in vivo literature review. J Pharm Sci. 2018 Dec;107(12):2983-2991.
2 Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics

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