Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010032)
Formula Reactant Raloxifene Product Raloxifene-6-sulfate
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010029 Raloxifene Raloxifen-4-glucoronide(M2) Conjugation - Glucuronidation Raloxifene [1], [2], [3]
MR010031 Raloxifene Raloxifene-6, 4-diglucuronide(M3) Conjugation - Glucuronidation Raloxifene [1], [2]
MR010030 Raloxifene Raloxifene-6-bate-glucuronide(M1) Conjugation - Glucuronidation Raloxifene [1], [2]
References
1 Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9
2 Determination of raloxifene and its glucuronides in human urine by liquid chromatography-tandem mass spectrometry assay
3 Pharmacokinetics of raloxifene and its clinical application

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