Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010035)
Formula
SVG example
Unclear
Reactant Dexibuprofen Product 3-Hydroxyibuprofen
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010034 Dexibuprofen 2-Hydroxyibuprofen Unclear - Unclear Dexibuprofen [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004641 Ibuprofen 3-Hydroxyibuprofen Oxidation - 3-hydroxylation Ibuprofen [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004642 3-Hydroxyibuprofen Carboxy-ibuprofen Oxidation - Dehydrogenation Ibuprofen [3], [2]
References
1 DrugBank(Pharmacology-Metabolism):Dexibuprofen
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
3 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.

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