Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010273)
Formula Reactant Mipomersen Product Mipomersen Metabolite M1
Reactant Info Product Info
Metabolic Enzyme Endonuclease (ENDO) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011064 Mipomersen Nucleotides Unclear - Unclear Mipomersen [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010274 Mipomersen Metabolite M1 Mipomersen Metabolite M2 Unclear - Unclear Mipomersen [2]
References
1 Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration-Approved Antisense Oligonucleotide Drugs
2 Clinical pharmacological properties of mipomersen (Kynamro), a second generation antisense inhibitor of apolipoprotein B

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