Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010449)
Formula	PPD Cleavage
	Reactant	PR-176	Product	Oprozomib Metabolite M3
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	peptidases (PPD)				DME Info
Metabolic Type	Other reaction - Cleavage

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR010448	Oprozomib	PR-176	Unclear - Unclear	Oprozomib	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR010451	PR-025	Oprozomib Metabolite M3	Unclear - Unclear	Oprozomib	[1]

References
1	In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s

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