Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010766)
Formula
CYP3A4 ...
SVG example
Unclear
Reactant Tiotropium Product N-methylscopine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010765 Tiotropium Dithienylglycolic Acid Unclear - Unclear Tiotropium [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005001 Tiotropium Bromide N-methylscopine Hydrolysis - Hydrolyzation Tiotropium Bromide [3]
References
1 Quantitative determination of pentazocine in plasma and of pentazocine and metabolites in urine
2 Tiotropium bromide. A review of its use as maintenance therapy in patients with COPD. Treat Respir Med. 2004;3(4):247-68.
3 Biochemical properties, pharmacokinetics and pharmacological response of tiotropium in chronic obstructive pulmonary disease patients

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