Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010774)
Formula
UGT2B7 ...
SVG example
O-glucuronidation
Reactant Nalmefene Product Nalmefene 3-O-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info
UDP-glucuronosyltransferase 1A8 (UGT1A8) DME Info
Metabolic Type Conjugation - O-glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010775 Nalmefene Nalmefene 3-O-sulfate Conjugation - Sulfation Nalmefene [1]
MR010771 Nalmefene Nornalmefene Oxidation - Dealkylation Nalmefene [2]
References
1 Isolation of a novel morphinan 3-O-diglucuronide metabolite from dog urine
2 LABEL:Nalmefene

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