Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010782)
Formula Reactant Zanubrutinib Metabolite M7/M8 Product Zanubrutinib Metabolite M4
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010781 Zanubrutinib Zanubrutinib Metabolite M7/M8 Unclear - Unclear zanubrutinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010797 Naloxone Naloxol Reduction - 6-ketoreduction Naloxone [2]
References
1 In vitro investigations into the roles of CYP450 enzymes and drug transporters in the drug interactions of zanubrutinib, a covalent Bruton's tyrosine kinase inhibitor
2 Metabolites of naloxone in human urine

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