Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011158)
Formula
SVG example
Hydroxylation
Reactant Antazoline M2 Product Antazoline A
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011157 Antazoline Antazoline M2 Oxidation - Hydroxylation Antazoline [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011161 Antazoline M2 Antazoline D Unclear - Unclear Antazoline [2]
MR011166 Antazoline M2 Antazoline M3 Conjugation - Glucuronidation Antazoline [2]
MR011167 Antazoline M2 Antazoline M5 Conjugation - Glucuronidation Antazoline [2]
MR011163 Antazoline M2 Antazoline MW299 Unclear - Unclear Antazoline [2]
MR011165 Antazoline M2 Antazoline MW361 Oxidation - Sulfoxidation Antazoline [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011159 Antazoline A Antazoline M6 Conjugation - Glucuronidation Antazoline [2]
MR011160 Antazoline A Antazoline MW487b Conjugation - Glucuronidation Antazoline [2]
References
1 Development and Performance Verification of the PBPK Model for Antazoline and Its Metabolite and Its Utilization for Pharmacological Hypotheses Formulating
2 Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry

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