Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011347)
Formula
SVG example
Unclear
Reactant NCX-4016 Product SA
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011346 NCX-4016 ASA Unclear - Unclear NCX-4016 [1]
MR011348 NCX-4016 HBA Unclear - Unclear NCX-4016 [1]
MR011349 NCX-4016 NCX4015 Unclear - Unclear NCX-4016 [1]
MR011344 NCX-4016 NCX4017 Unclear - Unclear NCX-4016 [1]
MR011345 NCX-4016 NCX4019 Unclear - Unclear NCX-4016 [1]
MR011343 NCX-4016 NCX4023 Unclear - Unclear NCX-4016 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002992 Aspirin Salicylic acid Unclear - Unclear Aspirin [2]
MR010983 Benzoic acid Salicylic acid Unclear - Unclear Benzoic acid [3]
MR006359 Salicin Salicylic acid Unclear Salicin [4]
MR010973 Salsalate Salicylic acid Unclear - Unclear Salsalate [5]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010984 Salicylic acid Beta-O-D-Glucosylsalcylic acid Unclear - Unclear Benzoic acid [3]
MR002995 Salicylic acid Gentistic acid Unclear - Unclear Aspirin [2]
MR006360 Salicylic acid Gentistic acid Unclear Salicin [4]
MR010985 Salicylic acid Methyl salicylate Unclear - Unclear Benzoic acid [3]
MR002993 Salicylic acid Phenolic glucuronide Conjugation - Glucuronidation Aspirin [2]
MR002994 Salicylic acid Salicylic acid acyl glucuronide Conjugation - Glucuronidation Aspirin [2]
MR010986 Salicylic acid Salicylic acid glucose ester Unclear - Unclear Benzoic acid [3]
MR002996 Salicylic acid Salicyluric acid Unclear - Unclear Aspirin [2]
MR006361 Salicylic acid Salicyluric acid Unclear Salicin [4]
⏷ Show the Full List of MR
References
1 Nitric oxide release and distribution following oral and intraperitoneal administration of nitroaspirin (NCX 4016) in the rat
2 Effect of common single-nucleotide polymorphisms in acetylsalicylic acid metabolic pathway genes on platelet reactivity in patients with diabetes Med Sci Monit. 2013 May 27;19:394-408. doi: 10.12659/MSM.883922.
3 Biosynthesis and metabolism of salicylic acid
4 Pharmacokinetics of salicin after oral administration of a standardised willow bark extract
5 AMPK: mediating the metabolic effects of salicylate-based drugs?

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