Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011432)
Formula Reactant Reduction of Desmethyl futibatinib Product Reduction hydrolysed desmethyl futibatinib
Reactant Info Product Info
Metabolic Type Other reaction - Hydration
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011428 Desmethyl futibatinib Reduction of Desmethyl futibatinib Unclear - Unclear TAS-120 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011431 Reduction of Desmethyl futibatinib Reduction of bisdesmethyl futibatinib Oxidation - O-demethylation TAS-120 [1]
References
1 Evaluation of the Mass Balance and Metabolic Profile of Futibatinib in Healthy Participants

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