Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011439)
Formula Reactant Monohydroxy futibatinib Product TAS-120 Metabolite P1
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011438 TAS-120 Monohydroxy futibatinib Unclear - Unclear TAS-120 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011441 Monohydroxy futibatinib Cysteine-conjugated monohydroxyl futibatinib Unclear - Unclear TAS-120 [1]
MR011440 Monohydroxy futibatinib Sulfate Monohydroxy futibatinib Conjugation - Sulfation TAS-120 [1]
References
1 Evaluation of the Mass Balance and Metabolic Profile of Futibatinib in Healthy Participants

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