Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011470)
Formula Reactant ABT-107 Product ABT-107 Metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 2J2 (CYP2J2) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011467 ABT-107 ABT-107 Metabolite M1 Unclear - Unclear ABT-107 [1]
MR011475 ABT-107 ABT-107 Metabolite M15/16 Unclear - Unclear ABT-107 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011474 ABT-107 Metabolite M2 ABT-107 Metabolite M13/14 Unclear - Unclear ABT-107 [1]
MR011471 ABT-107 Metabolite M2 ABT-107 Metabolite M3 Unclear - Unclear ABT-107 [1]
MR011473 ABT-107 Metabolite M2 ABT-107 Metabolite M7/9 Unclear - Unclear ABT-107 [1]
MR011472 ABT-107 Metabolite M2 ABT-107 Metabolite M8/10 Unclear - Unclear ABT-107 [1]
References
1 Species-dependent metabolism of a novel selective 7 neuronal acetylcholine receptor agonist ABT-107

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