Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011515)
Formula Reactant AMG 232 Product AMG 232 Metabolite M3
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011513 AMG 232 AMG 232 Metabolite M1 Unclear - Unclear AMG 232 [1]
MR011514 AMG 232 AMG 232 Metabolite M2 Unclear - Unclear AMG 232 [1]
MR011516 AMG 232 AMG 232 Metabolite M4/M5 Unclear - Unclear AMG 232 [1]
References
1 Pharmacokinetics and metabolism of AMG 232, a novel orally bioavailable inhibitor of the MDM2-p53 interaction, in rats, dogs and monkeys: in vitro-in vivo correlation

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