Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011604)
Formula	ADH4 Unclear
	Reactant	Tivantinib Metabolite M4	Product	Tivantinib Metabolite M6
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Alcohol dehydrogenase class-II (ADH4)				DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011603	Tivantinib	Tivantinib Metabolite M4	Unclear - Unclear	Tivantinib	[1]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011606	Tivantinib Metabolite M4	Tivantinib Metabolite M11	Oxidation - Oxidation	Tivantinib	[1]
MR011605	Tivantinib Metabolite M4	Tivantinib Metabolite M15,16	Unclear - Unclear	Tivantinib	[1]

References
1	Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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