Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011608)
Formula Reactant Tivantinib Metabolite M5 Product Tivantinib Metabolite M15,16
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011607 Tivantinib Tivantinib Metabolite M5 Unclear - Unclear Tivantinib [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011609 Tivantinib Metabolite M5 Tivantinib Metabolite M12 Oxidation - Oxidation Tivantinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011605 Tivantinib Metabolite M4 Tivantinib Metabolite M15,16 Unclear - Unclear Tivantinib [1]
References
1 Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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