Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011625)
Formula	Oxidation
	Reactant	MLN4924 Metabolite M3	Product	MLN4924 Metabolite M2
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Oxidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011624	MLN4924	MLN4924 Metabolite M3	Oxidation - Hydroxylation	MLN4924	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011623	MLN4924 Metabolite M1	MLN4924 Metabolite M2	Oxidation - Oxidation	MLN4924	[1]

References
1	Metabolism and Disposition of [(14)C]Pevonedistat, a First-in-Class NEDD8-Activating Enzyme Inhibitor, after Intravenous Infusion to Patients with Advanced Solid Tumors

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