Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011740)
Formula
CTSA ...
SVG example
Unclear
Reactant INX-189 Product INX-09054
Reactant Info Product Info
Metabolic Enzyme Cathepsin A (CTSA) DME Info
Carboxylesterase 1 (CES1) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011747 INX-189 1-Naphthol Unclear - Unclear INX-189 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011741 INX-09054 INX-09122 Unclear - Unclear INX-189 [1]
References
1 In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity

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