Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012026)
Formula Reactant M409-2 Product M395-1
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012023 Fruquintinib M409-2 Oxidation - Mono-oxidation fruquintinib [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012024 M409-2 M425-2 Unclear - Unclear fruquintinib [3]
MR012027 M409-2 M585 Unclear - Unclear fruquintinib [4]
References
1 A simple and rapid infrared-assisted self enzymolysis extraction method for total flavonoid aglycones extraction from Scutellariae Radix and mechanism exploration
2 Preclinical pharmacokinetics and disposition of a novel selective VEGFR inhibitor fruquintinib (HMPL-013) and the prediction of its human pharmacokinetics
3 Optical biosensor optimized for continuous in-line glucose monitoring in animal cell culture
4 Derivatization-free LC-MS/MS method for estrogen quantification in mouse brain highlights a local metabolic regulation after oral versus subcutaneous administration

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