Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012215)
Formula
SVG example
Di-O-desmethylation
Reactant TR-14081 Product TR-14331
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Metabolic Type Oxidation - Di-O-desmethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012214 TR-14035 TR-14081 Oxidation - O-desmethylation TR-14035 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012216 TR-14081 TR-14081 sulfate Conjugation - O-sulfate conjugation TR-14035 [1]
References
1 Pharmacokinetics and metabolism of TR-14035, a novel antagonist of a4ss1/a4ss7 integrin mediated cell adhesion, in rat and dog

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