Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR012331)
Formula	Unclear
	Reactant	DFdCDP		Product	DFdCTP
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001118	Gemcitabine Monophosphate	Gemcitabine diphosphate	Other reaction - Phosphorylation	Gemcitabine	[1]
MR012330	DFdCMP	DFdCDP	Unclear - Unclear	CO-101	[2]

References
1	Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2',2'-difluorodeoxyuridine and their nucleotides Br J Clin Pharmacol. 2018 Jun;84(6):1279-1289. doi: 10.1111/bcp.13557.
2	Phase I study of oral CP-4126, a gemcitabine derivative, in patients with advanced solid tumors

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