Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012747)
Formula Reactant L-A1Pyrroline-5-carboxylate Product L-Proline
Reactant Info Product Info
Metabolic Enzyme Pyrroline-5-carboxylate reductase 3 (PYCR3) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012746 L-Glutamyl-y-semialdehyde L-A1Pyrroline-5-carboxylate Unclear - Unclear Arginine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001526 1-pyrroline-5-carboxylic acid L-Proline Unclear L-glutamine [2]
MR003202 Pyr2C L-proline Unclear AK-41099 [3]
References
1 Arginine Metabolism Revisited
2 The Emerging Role of l-Glutamine in Cardiovascular Health and Disease Nutrients. 2019 Sep 4;11(9):2092. doi: 10.3390/nu11092092.
3 Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form. Biochem Biophys Res Commun. 2019 Aug 13;516(1):189-195.

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