Details of the Metabolic Reaction (MR)
| General Information of This Metabolic Reaction (MR) (ID: MR013128) | ||||||
|---|---|---|---|---|---|---|
| Formula |
  Deacetylation, hydroxylation,glucuronidation
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| Reactant | Trametinib Metabolite M2 | Product | Trametinib Metabolite M4 | |||
| Reactant Info | Product Info | |||||
| Metabolic Type | Multi-steps Reaction - Deacetylation, hydroxylation,glucuronidation | |||||
| Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||
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| Other MR(s) That Produce The Reactant of This MR | |||||||||||||||||||||||||||||
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| References | ||||||
|---|---|---|---|---|---|---|
| 1 | Trametinib, a first-in-class oral MEK inhibitor mass balance study with limited enrollment of two male subjects with advanced cancers | |||||
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