Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013480)
Formula
TK2
SVG example
Phosphorylation
Reactant Valaciclovir Product Acyclovir monophosphate
Reactant Info Product Info
Metabolic Enzyme Thymidine kinase 2 (TK2) DME Info
Metabolic Type Conjugation - Phosphorylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013483 Valaciclovir Acyclovir Unclear Valacyclovir Hydrochloride [1], [2]
MR013484 Valaciclovir L-valine Unclear Valacyclovir Hydrochloride [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013481 Acyclovir monophosphate Acyclovir diphosphate Conjugation - Phosphorylation Valacyclovir Hydrochloride [3]
References
1 Valacyclovir: a review of its antiviral activity, pharmacokinetic properties, and clinical efficacy
2 Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase
3 DrugBank(Pharmacology-Metabolism):Valacyclovir Hydrochloride

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