Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013685)
Formula
SVG example
Reactant Indocyanine green Product Enzalutamide metabolite M13
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013689 Indocyanine green Carboxyl metabolite enzalutamide (M1) Multi-steps Reaction - Amide Hydrolysis; Demethylation Enzalutamide [1], [2]
MR013693 Indocyanine green Enzalutamide metabolite M4 Unclear Enzalutamide [1]
MR008126 Indocyanine green Indocyanine green metabolite M1 Unclear - Unclear Indocyanine green [3]
MR008127 Indocyanine green Indocyanine green metabolite M2 Unclear - Unclear Indocyanine green [3]
MR008128 Indocyanine green Indocyanine green metabolite M3 Unclear - Unclear Indocyanine green [3]
MR008129 Indocyanine green Indocyanine green metabolite M4 Unclear - Unclear Indocyanine green [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013686 Enzalutamide metabolite M13 Enzalutamide metabolite M14 Conjugation - Cysteinylglycine conjugation Enzalutamide [1]
References
1 Absorption, Distribution, Metabolism, and Excretion of the Androgen Receptor Inhibitor Enzalutamide in Rats and Dogs
2 Pharmacokinetic Aspects of the Two Novel Oral Drugs Used for Metastatic Castration-Resistant Prostate Cancer: Abiraterone Acetate and Enzalutamide
3 Light-induced decomposition of indocyanine green

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