Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR014158)
Formula
SVG example
N-dealkylation
Reactant Baricitinib Product Baricitinib M3
Reactant Info Product Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014155 Baricitinib Baricitinib M1 Oxidation - Hydroxylation Baricitinib [1]
MR014173 Baricitinib Baricitinib M2 Oxidation - Hydroxylation Baricitinib [1]
MR014157 Baricitinib Baricitinib M5 Hydrolysis - Hydrosis Baricitinib [1]
MR014171 Baricitinib Baricitinib M6 Oxidation - Oxidation Baricitinib [1]
References
1 High resolution mass spectrometry-driven metabolite profiling of baricitinib to report its unknown metabolites and step-by-step reaction mechanism of metabolism

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