Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00012)
Xenobiotics Name
Carmustine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
2578
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Porphobilinogen synthase (ALAD) DME Info Homo sapiens [1]
Aromatase (CYP19A1) DME Info Homo sapiens [1]
Glutathione reductase (GSR) DME Info Homo sapiens [2]
Iduronate 2-sulfatase (IDS) DME Info Homo sapiens [1]
S-adenosylmethionine synthase 1 (MAT1A) DME Info Homo sapiens [1]
Mevalonate pyrophosphate decarboxylase (MPD) DME Info Homo sapiens [1]
Phosphorylcholine transferase A (PCYT1A) DME Info Homo sapiens [1]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [3]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Glutathione reductase (GSR) DME Info IC50 = 8.1 microM [2]
References
1 Gene expression profile induced by BCNU in human glioma cell lines with differential MGMT expression. J Neurooncol. 2005 Jul;73(3):189-98.
2 Synthesis and evaluation of the antiparasitic activity of bis-(arylmethylidene) cycloalkanones. Eur J Med Chem. 2014 Jan;71:282-9.
3 Proline analogue of nitrosourea as a new cytotoxic prodrug. Arch Pharm (Weinheim). 2009 Nov;342(11):632-9.

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