Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00046)
Xenobiotics Name
Ifosfamide
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
3690
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytosolic branched aminotransferase (BCAT1) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [1]
Iduronate 2-sulfatase (IDS) DME Info Homo sapiens [1]
Quinone reductase 1 (NQO1) DME Info Homo sapiens [1]
Steroid 5-alpha-reductase 3 (SRD5A3) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Aldo-keto reductase 1C2 (AKR1C2) DME Info Homo sapiens [1]
Asparagine synthetase (ASNS) DME Info Homo sapiens [1]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [1]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [2]
Glutathione reductase (GSR) DME Info Homo sapiens [1]
Metallothionein-2A (MT2A) DME Info Homo sapiens [1]
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [1]
References
1 Transcriptomics hit the target: monitoring of ligand-activated and stress response pathways for chemical testing. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):7-18.
2 Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor. Cancer Chemother Pharmacol. 2009 Jun;64(1):35-43.

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