Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00126)
Xenobiotics Name
Raloxifene hydrochloride
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
54900
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Asparagine synthetase (ASNS) DME Info Homo sapiens [1]
Cytochrome P450 2C8 (CYP2C8) DME Info Homo sapiens [1]
Delta(24)-sterol reductase (DHCR24) DME Info Homo sapiens [1]
Methylenetetrahydrofolate reductase (MTHFR) DME Info Homo sapiens [2], [1]
Nitric oxide synthase inducible (NOS2) DME Info Homo sapiens [1]
Phosphodiesterase 5A (PDE5A) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Catalase (CAT) DME Info Homo sapiens [1]
Metallothionein-2A (MT2A) DME Info Homo sapiens [1]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [1]
References
1 Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells. Mutagenesis. 2011 Sep;26(5):593-604.
2 Quercetin-induced downregulation of phospholipase D1 inhibits proliferation and invasion in U87 glioma cells. Biochem Biophys Res Commun. 2011 Sep 9;412(4):710-5.

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