Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00181)
Xenobiotics Name
Dasatinib
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
3062316
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Alanyl aminopeptidase (ANPEP) DME Info Homo sapiens [1]
Aldehyde oxidase (AOX1) DME Info Homo sapiens [2]
Dihydrofolate reductase (DHFR) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Aldo-keto reductase 1C3 (AKR1C3) DME Info Homo sapiens [2]
Aldehyde dehydrogenase 1 (ALDH1) DME Info Homo sapiens [2]
Aldehyde dehydrogenase 2 (ALDH2) DME Info Homo sapiens [2]
Asparagine synthetase (ASNS) DME Info Homo sapiens [2]
Carboxylesterase 1 (CES1) DME Info Homo sapiens [2]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [2]
Short-chain dehydrogenase/reductase retSDR1 (DHRS3) DME Info Homo sapiens [2]
Dipeptidyl peptidase IV (DPP4) DME Info Homo sapiens [2]
References
1 The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils. Blood. 2008 Mar 15;111(6):3097-107.
2 Dasatinib reverses cancer-associated fibroblasts (CAFs) from primary lung carcinomas to a phenotype comparable to that of normal fibroblasts. Mol Cancer. 2010 Jun 27;9:168.

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