Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00235)
Xenobiotics Name
Budesonide
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
2462
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytosolic phospholipase A2 (PLA2G4A) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [2]
Cytochrome P450 3A5 (CYP3A5) DME Info Homo sapiens [3], [4]
Metallothionein-2A (MT2A) DME Info Homo sapiens [5]
References
1 Comparison of in vitro-activity of commonly used topical glucocorticoids on cytokine- and phospholipase inhibition. Eur J Med Res. 2004 Aug 31;9(8):383-90.
2 Expression and regulation of the bile acid transporter, OSTalpha-OSTbeta in rat and human intestine and liver. Biopharm Drug Dispos. 2009 Jul;30(5):241-58.
3 Regulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells. J Pharmacol Exp Ther. 2003 Feb;304(2):745-52.
4 Regulation of CYP3A genes by glucocorticoids in human lung cells. F1000Res. 2013 Aug 13;2:173.
5 Interaction between glucocorticoids and beta2-agonists: alpha and beta glucocorticoid-receptor mRNA expression in human bronchial epithelial cells. Biochem Pharmacol. 1998 Dec 15;56(12):1561-9.

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