Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00318)
Xenobiotics Name	Phenelzine sulfate
Xenobiotics Type	Pharmaceutical Agent(s)
Classification	Approved/Marketed Drug
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=61100"></iframe>
Structure	3D MOL	2D MOL
PubChem CID	61100
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
	Cytochrome P450 2C8 (CYP2C8)	DME Info	Homo sapiens	[1]
	Cytochrome P450 3A4 (CYP3A4)	DME Info	Homo sapiens	[2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data	Cytochrome P450 2C8 (CYP2C8)	DME Info	Ki = 1.2 microM	[1]
Xenobiotics-DME Activity Data	Cytochrome P450 3A4 (CYP3A4)	DME Info	IC50 = 2 microM	[2]

References
1	Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Curr Drug Metab. 2005 Oct;6(5):413-54.
2	Mechanism-based inactivation of human cytochrome P4502C8 by drugs in vitro. J Pharmacol Exp Ther. 2004 Dec;311(3):996-1007.

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