Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00374)
Xenobiotics Name
Pazopanib
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
10113978
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [1]
Cytochrome P450 2C8 (CYP2C8) DME Info Homo sapiens [2]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [2]
References
1 Human drug metabolism genes in parathion-and estrogen-treated breast cells. Int J Mol Med. 2007 Dec;20(6):875-81.
2 Environmental pollutants parathion, paraquat and bisphenol A show distinct effects towards nuclear receptors-mediated induction of xenobiotics-metabolizing cytochromes P450 in human hepatocytes. Toxicol Lett. 2015 Oct 1;238(1):43-53.

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