Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00400)
Xenobiotics Name
Warfarin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=54678486"></iframe>
3D MOL 2D MOL
PubChem CID
54678486
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME Info Homo sapiens [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 2C9 (CYP2C9) DME Info Ki = 20 microM [1]
References
1 Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors. J Med Chem. 2004 Feb 12;47(4):907-14.
2 A new in vitro method for identifying chemical sensitizers combining peptide binding with ARE/EpRE-mediated gene expression in human skin cells. Cutan Ocul Toxicol. 2010 Sep;29(3):171-92.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.