Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00401)
Xenobiotics Name
Beta carotene
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
5280489
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aldehyde dehydrogenase 7 (ALDH7) DME Info Homo sapiens [1]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Alcohol dehydrogenase class-I alpha (ADH1A) DME Info Homo sapiens [1]
Alcohol dehydrogenase class-III (ADH5) DME Info Homo sapiens [1]
Beta,beta-carotene 15,15'-dioxygenase (BCO1) DME Info Homo sapiens [2]
Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info Homo sapiens [3], [2]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [1]
Cytochrome P450 3A43 (CYP3A43) DME Info Homo sapiens [1]
Nitric oxide synthase brain (NOS1) DME Info Homo sapiens [1]
Transglutaminase H (TGM2) DME Info Homo sapiens [1]
References
1 Beta-carotene and apocarotenals promote retinoid signaling in BEAS-2B human bronchioepithelial cells. Arch Biochem Biophys. 2006 Nov 1;455(1):48-60.
2 Beta-Carotene conversion into vitamin A in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3562-9.
3 Co-cultures of enterocytes and hepatocytes for retinoid transport and metabolism. Toxicol In Vitro. 2012 Dec;26(8):1256-64.

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