Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00462)
Xenobiotics Name
Bambuterol
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
54766
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Acetylcholinesterase (ACHE) DME Info Homo sapiens [1], [2]
Butyrylcholine esterase (BCHE) DME Info Homo sapiens [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Acetylcholinesterase (ACHE) DME Info IC50 = 30 microM [1], [2]
Butyrylcholine esterase (BCHE) DME Info IC50 = 0.003 microM [2]
References
1 Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease. Eur J Med Chem. 2017 May 26;132:294-309.
2 Design, synthesis and biological evaluation of bambuterol analogues as novel inhibitors of butyrylcholinesterase. Eur J Med Chem. 2017 Jan 27;126:61-71.

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