Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO00466) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Demecolcine
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| Xenobiotics Type |
Pharmaceutical Agent(s)
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| Classification |
Approved/Marketed Drug
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| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=220401"></iframe>
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| 3D MOL | 2D MOL | |||||
| PubChem CID | ||||||
| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Dihydrofolate reductase (DHFR) | DME Info | Homo sapiens | [1] | |||
| Adenosine 5'-monophosphoramidase (HINT1) | DME Info | Homo sapiens | [1] | |||
| Methionine-tRNA ligase mitochondrial (MARS2) | DME Info | Homo sapiens | [1] | |||
| Phosphoribosylformylglycinamidine synthase (PFAS) | DME Info | Homo sapiens | [1] | |||
| Phosphoglucomutase 1 (PGM1) | DME Info | Homo sapiens | [1] | |||
| Selenocysteine lyase (SCLY) | DME Info | Homo sapiens | [1] | |||
| DME(s) Induced by This Xenobiotics | ||||||
| Cytosolic branched aminotransferase (BCAT1) | DME Info | Homo sapiens | [1] | |||
| Cytochrome P450 4F2 (CYP4F2) | DME Info | Homo sapiens | [1] | |||
| Leukotriene B4 omega-hydroxylase (CYP4F3) | DME Info | Homo sapiens | [1] | |||
| L-glutamine amidohydrolase (GLS) | DME Info | Homo sapiens | [1] | |||
| Iduronate 2-sulfatase (IDS) | DME Info | Homo sapiens | [1] | |||
| Metallothionein-2A (MT2A) | DME Info | Homo sapiens | [1] | |||
| Ecto-5'-nucleotidase (NT5E) | DME Info | Homo sapiens | [1] | |||
| Putrescine acetyltransferase (SSAT1) | DME Info | Homo sapiens | [1] | |||
| Tryptophan oxygenase (TRPO) | DME Info | Homo sapiens | [1] | |||
| References | ||||||
| 1 | Characterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells. Arch Toxicol. 2013 Nov;87(11):1999-2012. | |||||
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