Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00706)
Xenobiotics Name
Tripterine
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Preclinical/Patented Drug
Structure
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3D MOL 2D MOL
PubChem CID
122724
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Aldo-keto reductase 1C2 (AKR1C2) DME Info Homo sapiens [1], [2]
Cytidine aminohydrolase (CDA) DME Info Homo sapiens [2]
Prostaglandin G/H synthase 1 (COX-1) DME Info Homo sapiens [3]
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [1]
References
1 From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch Toxicol. 2014 Jul;88(7):1451-68.
2 A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.
3 Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol. 2017 Feb;91(2):839-864.

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