Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00707)
Xenobiotics Name
JTE-522
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Preclinical/Patented Drug
Structure
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3D MOL 2D MOL
PubChem CID
159271
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Prostaglandin G/H synthase 2 (COX-2) DME Info IC50 = 0.085 microM [1]
References
1 4-(4-cycloalkyl/aryl-oxazol-5-yl)benzenesulfonamides as selective cyclooxygenase-2 inhibitors: enhancement of the selectivity by introduction of a fluorine atom and identification of a potent, highly selective, and orally active COX-2 inhibitor JTE-522(1). J Med Chem. 2002 Mar 28;45(7):1511-7.

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